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Nitrofurazone

Chemical name: 5-Nitro-2-furaldehyde semicarbazone
Molecular formula: C6H6N4O4
Molecular weight: 198.14
CAS: 59-87-0
Structural formula:

Specification:
A: In accordance with Drug standard of the Ministry of Health of PRC (1989 edition)
Appearance: Bright-yellow crystalline powder.
Melting point: 236~240℃
pH: 5.5~7.0
Chloride: ≤0.014%
Sulfate: ≤0.04%
Loss on drying: ≤0.5%
Residue on ignition: ≤0.1%
Assay: 97.0~103.0%
Total aerobic microbial count: Not more than 103cfu/g
Total yeast and mold count: Not more than 102cfu/g
Staphylococcus aureus: Should be absent in 1g.
Pseudomonas aeruginosa: Should be absent in 1g.
E.coli: Should be absent in 1g.
B: In accordance with USP
Appearance: Lemon yellow crystalline powder.
pH: 5.0~7.5
Loss on drying: ≤0.5%
Residue on ignition: ≤0.1%
Assay: 98.0~102.0% of C6H6N4O4 calculated on dried substance.
(5-nitrofurfural-2-yl) methylene diacetate: ≤0.5%
1,2-bis[(5-nitrofuran-2-yl) methylidene] diazane: ≤0.5%
Any individual unspecified impurity: ≤0.1%
Total impurities: ≤2.0%
C: In accordance with EP
Appearance: Yellow or brownish-yellow crystalline powder.
pH: 5.0~7.0
Loss on drying: ≤0.5%
Sulfated ash: ≤0.1%
Assay(calculated on dried basis): 97.0~103.0%
(5-nitrofurfural-2-yl) methylene diacetate: ≤0.5%
1,2-bis[(5-nitrofuran-2-yl) methylidene] diazane: ≤0.5%
Any individual unspecified impurity: ≤0.10%
Total impurities: ≤2.0%
 
Packing size: 25Kg/drum
Authentication code: Guo Yao Zhun Zi H37022206
Indications: disinfectant and antiseptic used for local or surface sterilization.

 
 
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